If you expect the best of the best, enjoy outstanding service and experience luxury like no other in Brandywine 5-star properties. Find the best deals and unwind in style at iconic five star hotels in Brandywine. These world class Brandywine hotels offer luxurious accommodations with premium locations. Check out this list of Brandywine ultra-opulent hotels to pamper yourself. From modern to classic the Brandywine area hotels offer something for your specific liking.